Dietary fat increases vitamin D-3 absorption.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The researchers tested the hypotheses that absorption of vitamin D-3 is greater when the supplement is taken with a meal containing fat than with a fat-free meal and that absorption is greater when the fat in the meal has a higher monounsaturated-to-polyunsaturated fatty acid ratio (MUFA:PUFA).

Why It Was Studied

The plasma 25-hydroxyvitamin D response to supplementation with vitamin D varies widely, but vitamin D absorption differences based on diet composition is poorly understood.

Means were compared with two-tailed t tests for independent samples.

Who Took Part

According to the abstract, 50 men were involved.

By PubMed's age tags, the people studied were middle-aged adults and older adults, both men and women.

How the Study Was Run

The design is described as randomized and single-blind.

The men were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

In this single-blind Vitamin D, K2, Magnesium and Zinc study one party knew the assignments and the other did not.

What Was Measured

Means were compared with two-tailed t tests for independent samples.

Group differences in vitamin D-3 absorption across the measurement time points were examined by analysis of variance with the repeated measures subcommand of the general linear models procedure.

PubMed files the paper under topics including Cholecalciferol, Dietary Fats, Dietary Proteins, Dietary Supplements, Fatty Acids, Monounsaturated, Fatty Acids, Unsaturated and Meals.

The authors tagged it with the keywords Absorption, Healthy adults, Meal conditions, Vitamin D-3 and Vitamin D-3 supplementation.

What This Means in Plain Language

The paper is a randomized and single-blind study of Vitamin D, K2, Magnesium and Zinc in 50 men.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2015 (Journal of the Academy of Nutrition and Dietetics), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.