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Randomised controlled trial of daily versus stoss vitamin D therapy in Aboriginal children.

Plain-language guide to PMID 25523190 (2015): pilot randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
25523190
Journal
Journal of paediatrics and child health
Year
2015
Study type
Randomized Controlled Trial
Authors
Tan JK et al. (4 authors)
DOI
10.1111/jpc.12781

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The prevalence of vitamin D deficiency has risen in countries with a high ultraviolet index and sunny environment such as Australia.

There is lack of information on vitamin D status and best possible therapy in Australian Aboriginal children.

Who Took Part

PubMed indexes the participants as young children and children, both men and women.

Participants were recruited from a metropolitan area (31' S) and a rural area (17' S).

How the Study Was Run

In design terms this was a randomized and pilot study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.

Biochemical and clinical parameters such as 25(OH)D, alkaline phosphatase, calcium and sun exposure were collected.

What Was Measured

Topics PubMed links to this paper include Calcifediol, Dietary Supplements, Pilot Projects, Vitamin D Deficiency and Western Australia.

Author keywords: children, indigenous and stoss therapy.

What This Means in Plain Language

The paper is a randomized and pilot study of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2015 (Journal of paediatrics and child health), a journal based in Australia.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.