Subjective response to nicotine by menstrual phase.

What Was Tested

This randomized controlled trial looks at Therapeutic nicotine (patch, non-peptide).

The researchers sought to examine the role of menstrual phase on response to nicotine during acute smoking abstinence.

Why It Was Studied

The luteal menstrual phase might be a favorable time for smoking cessation when non-nicotine interventions (e.g. counseling, bupropion) are used, whereas the follicular menstrual phase appears favorable when nicotine interventions are used.

Thus, there may be an interaction between menstrual phase and response to nicotine.

Who Took Part

By PubMed's age tags, the people studied were teenagers, young adults and adults, women only.

During the sessions, nicotine nasal spray was administered, and participants provided a series of subjective assessments.

How the Study Was Run

The researchers set it up as a randomized and crossover study.

Because people in this Therapeutic nicotine (patch, non-peptide) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

In the crossover set-up each of the participants took both Therapeutic nicotine (patch, non-peptide) and the comparison in turn, acting as their own control.

What Was Measured

The subject headings attached to it are Follicular Phase, Luteal Phase, Nicotine, Nicotinic Agonists and Smoking.

The authors tagged it with the keywords Addiction, Hormones and Menstrual cycle.

What This Means in Plain Language

The paper is a randomized and crossover study of Therapeutic nicotine (patch, non-peptide).

The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2015 (Addictive behaviors), a journal based in England.

More context: the Therapeutic nicotine (patch, non-peptide) compound page, all human trials.