[Vitamin D deficiency in pregnancy and its impact on the fetus, the newborn and in childhood].

What It Covers

This review looks at Vitamin D, K2, Magnesium and Zinc.

Vitamin D deficiency (VDD) in pregnant women and their children is an important health problem with severe consequences for the health of both.

Why It Was Studied

Original and review articles, and consensus documents with elevated level of evidence for VDD-related clinical decisions on the health of pregnant women and their children, as well as articles on the influence of ViD on epigenetic mechanisms of fetal programming of chronic diseases in adulthood were selected among articles published on PubMed over the last 20 years, using the search term VitD status, in combination with Pregnancy, Offspring health, Child outcomes, and Programming.

The following items were analyzed: ViD physiology and metabolism, risk factors for VDD and implications in pregnancy, lactation and infancy, concentration cutoff to define VDD, the variability of methods for VDD detection, recommendations on ViD replacement in pregnant women, the newborn and the child, and the epigenetic influence of ViD.

Who the Included Studies Covered

The age groups tagged for this paper are children, women only.

What Was Measured

Original and review articles, and consensus documents with elevated level of evidence for VDD-related clinical decisions on the health of pregnant women and their children, as well as articles on the influence of ViD on epigenetic mechanisms of fetal programming of chronic diseases in adulthood were selected among articles published on PubMed over the last 20 years, using the search term VitD status, in combination with Pregnancy, Offspring health, Child outcomes, and Programming.

PubMed files the paper under topics including Fetal Diseases, Practice Guidelines as Topic, Pregnancy Complications, Risk Factors and Vitamin D Deficiency.

Author keywords: Children, Criança, Fetal programming, Feto, Fetus and Gestação.

What This Means in Plain Language

This is a review of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2017 (Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo), a journal based in Brazil.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.