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The high prevalence of hypovitaminosis D in China: a multicenter vitamin D status survey.
Plain-language guide to PMID 25715263 (2015): multicenter observational study of Vitamin D, K2, Magnesium and Zinc in 2173 adults.
Key Facts
- PMID
- 25715263
- Journal
- Medicine
- Year
- 2015
- Study type
- Observational Study
- Authors
- Yu S et al. (15 authors)
- DOI
- 10.1097/MD.0000000000000585
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as an observational study.
The objective of this multicenter study was to determine the vitamin D status and prevalence of vitamin D deficiency by using a reliable method in 5 large cities in China.
Why It Was Studied
Vitamin D deficiency, which is usually detected by using immunoassays or the more reliable liquid chromatography tandem mass spectrometry (LC-MS/MS) methods, has recently been considered a public health problem worldwide.
However, the vitamin D status in Chinese populations, as measured using the LC-MS/MS method, is not available.
Who Took Part
According to the abstract, 2173 adults were involved.
PubMed indexes the participants as teenagers, young adults, adults and middle-aged adults, both men and women.
From May 1 to September 31, 2013, the researchers conducted a multicenter study on 2173 apparently healthy adults who were recruited from 5 Chinese cities.
How the Study Was Run
In design terms this was a multicenter study.
More than one site took part, so the adults came from several places.
The 25-hydroxyvitamin D 25OHD2 and 25OHD3 levels were measured using the LC-MS/MS method.
What Was Measured
However, the vitamin D status in Chinese populations, as measured using the LC-MS/MS method, is not available.
Intact parathyroid hormone (iPTH), calcium, phosphorus, and alkaline phosphate levels were also measured using an automatic analyzer.
The subject headings attached to it are Age Factors, China, Chromatography, Liquid, Healthy Volunteers, Mass Spectrometry, Prevalence and Vitamin D.
What This Means in Plain Language
The paper is a multicenter study of Vitamin D, K2, Magnesium and Zinc in 2173 adults.
With several hundred people or more, it is a fairly large study for this kind of research.
The publication is from 2015 (Medicine), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.