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Efficacy, Safety, and Predictors of Intradiscal Methylene Blue Injection for Discogenic Low Back Pain: Results of a Multicenter Prospective Clinical Series
Plain-language guide to PMID 25753429 (2016): randomized and double-blind clinical trial study of Methylene blue (non-peptide stack partner).
Key Facts
- PMID
- 25753429
- Journal
- Pain practice : the official journal of World Institute of Pain
- Year
- 2016
- Study type
- Clinical Trial
- Authors
- Kallewaard JW et al. (6 authors)
- DOI
- 10.1111/papr.12283
What This Study Did, in Plain Language
What Was Tested
This clinical trial paper looks at Methylene blue (non-peptide stack partner).
A substantial part of chronic LBP is attributable to degenerative changes in the intervertebral disc.
Who Took Part
The age groups tagged for this paper are adults, middle-aged adults and older adults, both men and women.
Prospective clinical study of intradiscal methylene blue injection for the treatment of lumbar discogenic pain.
Patients were selected on clinical criteria, magnetic resonance imaging, and a positive provocative discogram.
How the Study Was Run
The design is described as randomized, double-blind and pilot.
Because people in this Methylene blue (non-peptide stack partner) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
As a double-blind Methylene blue (non-peptide stack partner) study, the assignments were hidden from both participants and investigators until the end.
It is described as a pilot, a small early test of whether a larger Methylene blue (non-peptide stack partner) study would be practical.
What Was Measured
PubMed files the paper under topics including Intervertebral Disc, Intervertebral Disc Displacement, Low Back Pain, Methylene Blue, Netherlands, Pilot Projects and Quality of Life.
Author keywords: chronic pain and refractory pain.
What This Means in Plain Language
The paper is a randomized, double-blind and pilot study of Methylene blue (non-peptide stack partner).
Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2016 (Pain practice : the official journal of World Institute of Pain), a journal based in United States.
More context: the Methylene blue (non-peptide stack partner) compound page, all human trials.
Our Notes on the Compound
Methylene blue (non-peptide stack partner): Described as an electron cycler, not just a dye.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.