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Calcium plus vitamin D supplementation affects pregnancy outcomes in gestational diabetes: randomized, double-blind, placebo-controlled trial.
Plain-language guide to PMID 25790761 (2016): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.
Key Facts
- PMID
- 25790761
- Journal
- Public health nutrition
- Year
- 2016
- Study type
- Randomized Controlled Trial
- Authors
- Karamali M et al. (4 authors)
- DOI
- 10.1017/S1368980015000609
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.
The present study was designed to assess the effects of Ca+vitamin D supplementation on pregnancy outcomes in women with gestational diabetes mellitus (GDM).
Who Took Part
PubMed indexes the participants as teenagers, young adults and adults, women only.
A randomized, double-blind, placebo-controlled trial was conducted among sixty women with GDM.
Participants were divided into two groups to receive Ca+vitamin D supplements or placebo.
How the Study Was Run
The researchers set it up as a randomized, double-blind and placebo-controlled study.
The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.
A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.
A urban community setting in Arak, Iran.
Sixty women with GDM and their newborns, living in Arak, Iran were enrolled.
What Was Measured
Topics PubMed links to this paper include Blood Glucose, Body Mass Index, Calcium, Dietary, Cesarean Section, Cholecalciferol, Diabetes, Gestational and Dietary Supplements.
Author keywords: Gestational diabetes mellitus, Pregnancy outcomes, Supplementation and Vitamin D.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.
The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2016 (Public health nutrition), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.