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Effects of vitamin D-fortified low fat yogurt on glycemic status, anthropometric indexes, inflammation, and bone turnover in diabetic postmenopausal women: A randomised controlled clinical trial.

Plain-language guide to PMID 25794439 (2016): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 2 patients.

Key Facts

PMID
25794439
Journal
Clinical nutrition (Edinburgh, Scotland)
Year
2016
Study type
Randomized Controlled Trial
Authors
Jafari T et al. (8 authors)
DOI
10.1016/j.clnu.2015.02.014

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Low levels of serum 25-hydroxy vitamin D (25(OH)D) are common in type 2 diabetic patients and cause several complications particularly, in postmenopausal women due to their senile and physiological conditions.

This study aimed to assess the effects of vitamin D-fortified low fat yogurt on glycemic status, anthropometric indexes, inflammation, and bone turnover in diabetic postmenopausal women.

Who Took Part

According to the abstract, 2 patients were involved.

PubMed indexes the participants as middle-aged adults, women only.

How the Study Was Run

The design is described as randomized, double-blind, placebo-controlled and parallel-group.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the patients and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

The Vitamin D, K2, Magnesium and Zinc group and the comparison group ran side by side rather than switching.

What Was Measured

The subject headings attached to it are Biomarkers, Blood Glucose, Body Mass Index, Bone Remodeling, Cholesterol, HDL, Cholesterol, LDL and Cytokines.

Author keywords: Bone turnover, Glycemic status, Inflammation, Low fat yogurt, Type 2 diabetes mellitus and Vitamin D fortification.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 2 patients.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2016 (Clinical nutrition (Edinburgh, Scotland)), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.