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Exercise and vitamin D in fall prevention among older women: a randomized clinical trial.

Plain-language guide to PMID 25799402 (2015): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
25799402
Journal
JAMA internal medicine
Year
2015
Study type
Randomized Controlled Trial
Authors
Uusi-Rasi K et al. (7 authors)
DOI
10.1001/jamainternmed.2015.0225
Registered trial
NCT00986466

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Who Took Part

The age groups tagged for this paper are older adults and people over 80, women only.

Participants were 409 home-dwelling women 70 to 80 years old.

The main inclusion criteria were at least 1 fall during the previous year, no use of vitamin D supplements, and no contraindication to exercise.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

A 2-year randomized, double-blind, placebo-controlled vitamin D and open exercise trial conducted between April 2010 and March 2013 in Tampere, Finland.

What Was Measured

PubMed files the paper under topics including Accidental Falls, Bone Density, Exercise Therapy, Independent Living, Muscle Strength, Postural Balance and Trauma Severity Indices.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 11 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2015 (JAMA internal medicine), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.