Effects of vitamin D on blood pressure and cardiovascular risk factors: a randomized controlled trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc in the context of low blood pressure and orthostatic hypotension.

The researchers aimed to evaluate whether vitamin D supplementation affects 24-hour systolic ambulatory BP monitoring values and cardiovascular risk factors.

Why It Was Studied

The Styrian Vitamin D Hypertension Trial is a single-center, double-blind, placebo-controlled study conducted from June 2011 to August 2014 at the endocrine outpatient clinic of the Medical University of Graz, Austria.

The researchers enrolled 200 study participants with arterial hypertension and 25-hydroxyvitamin D levels below 30 ng/mL.

Who Took Part

The abstract describes 200 participants taking part.

PubMed indexes the participants as middle-aged adults and older adults, both men and women.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

What Was Measured

The researchers enrolled 200 study participants with arterial hypertension and 25-hydroxyvitamin D levels below 30 ng/mL.

Primary outcome measure was 24-hour systolic BP.

The subject headings attached to it are Austria, Blood Pressure, Blood Pressure Determination, Cardiovascular Diseases, Dietary Supplements, Hospitals, University and Hypertension.

The authors tagged it with the keywords cholecalciferol, placebo, randomized controlled trial and vitamin D.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 200 participants in people with low blood pressure and orthostatic hypotension.

The publication is from 2015 (Hypertension (Dallas, Tex. : 1979)), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Low blood pressure and orthostatic hypotension research.