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Vitamin D Status Is Positively Associated with Calcium Absorption among Postmenopausal Thai Women with Low Calcium Intakes.
Plain-language guide to PMID 25809682 (2015): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84) in 19 women.
Key Facts
- PMID
- 25809682
- Journal
- The Journal of nutrition
- Year
- 2015
- Study type
- Randomized Controlled Trial
- Authors
- Sirichakwal PP et al. (6 authors)
- DOI
- 10.3945/jn.114.207290
- Registered trial
- NCT02291315
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84) in this randomized controlled trial publication.
The objective of this study was to evaluate fractional calcium absorption from a green leafy vegetable vs. milk in relation to vitamin D status.
Why It Was Studied
Few data exist on the ability of postmenopausal women to absorb calcium from diets habitually low in calcium.
Who Took Part
The study group was 19 women.
By PubMed's age tags, the people studied were middle-aged adults and older adults, women only.
Women received intravenous ⁴²Ca with the first test meal.
How the Study Was Run
The design is described as randomized.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Fractional calcium absorption was measured using a triple stable calcium isotope method based on isotope recovery in a 28-h urine collection.
Two extrinsically labeled test meals were ingested in random order: a green leafy vegetable (cassia) ingested along with ⁴³Ca or a glass of milk containing ⁴⁴Ca.
What Was Measured
The subject headings attached to it are Aging, Biomarkers, Calcium Isotopes, Calcium, Dietary, Cassia, Diet and Intestinal Absorption.
Author keywords: bioavailability, calcium absorption, parathyroid hormone, postmenopausal women, stable isotope and vitamin D.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84) in 19 women.
With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.
The abstract goes on to report its results in about 6 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2015 (The Journal of nutrition), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Parathyroid Hormone (PTH 1-84) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.