Vitamin D status in Well-Controlled Caucasian HIV Patients in Relation to Inflammatory and Metabolic Markers--A Cross-Sectional Cohort Study in Sweden.

What Was Tested

This observational study looks at Vitamin D, K2, Magnesium and Zinc.

To study vitamin D (25OH D3 ) in relation to (i) microbial translocation (ii) systemic inflammation and (iii) blood lipid markers, in Caucasian, well-controlled HIV patients and healthy controls, plasma and serum samples from n = 97 male, HIV patients on HAART with immeasurable viral load (<20 copies/ml) since median 6.5 years and no concurrent inflammatory or infectious disease and n = 30 healthy controls were analysed for (i) LPS; (ii) sCD14, hsCRP, IL-4, IL-6, IL-10, IL-17, MCP-1 and IFN-γ; as well as (iii) blood lipids.

Vitamin D levels were similarly distributed and equally low in both HIV patients and controls.

Who Took Part

PubMed indexes the participants as adults and middle-aged adults, men only.

What Was Measured

To study vitamin D (25OH D3 ) in relation to (i) microbial translocation (ii) systemic inflammation and (iii) blood lipid markers, in Caucasian, well-controlled HIV patients and healthy controls, plasma and serum samples from n = 97 male, HIV patients on HAART with immeasurable viral load (<20 copies/ml) since median 6.5 years and no concurrent inflammatory or infectious disease and n = 30 healthy controls were analysed for (i) LPS; (ii) sCD14, hsCRP, IL-4, IL-6, IL-10, IL-17, MCP-1 and IFN-γ; as well as (iii) blood lipids.

Vitamin D levels were similarly distributed and equally low in both HIV patients and controls.

PubMed files the paper under topics including Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Apolipoproteins B, Biomarkers, Cholesterol, Cohort Studies and Cross-Sectional Studies.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc.

The publication is from 2015 (Scandinavian journal of immunology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.