Assessment of the safety and efficacy of topical copper chlorophyllin in women with photodamaged facial skin.

What Was Tested

Researchers studied Copper (Supplement) in this randomized controlled trial publication.

Chronic exposure to the sun causes the skin to prematurely age.

Photodamaged skin is characterized by progressive damage to the dermal extracellular matrix with loss of collagen and degradation of elastin.

Who Took Part

PubMed indexes the participants as adults, middle-aged adults and older adults, women only.

Clinical assessments were performed at screening/baseline and at week 8.

Standardized digital photographs were taken and self-assessment questionnaires were conducted.

How the Study Was Run

The design is described as randomized, double-blind and pilot.

The participants were allocated by chance, so the Copper (Supplement) group and the comparison group should start out alike.

Neither the participants nor the staff measuring them knew who was on Copper (Supplement), so expectations could not easily colour the readings.

It is described as a pilot, a small early test of whether a larger Copper (Supplement) study would be practical.

What Was Measured

Salts of copper chlorophyllin complex are semi-synthetic naturally derived compounds with anti-oxidant and wound healing activity that has not been previously tested in photodamaged skin.

Topics PubMed links to this paper include Administration, Topical, Chlorophyllides, Dermatologic Agents, Face, Pilot Projects, Radiation-Protective Agents and Self-Assessment.

What This Means in Plain Language

The paper is a randomized, double-blind and pilot study of Copper (Supplement).

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2015 (Journal of drugs in dermatology : JDD), a journal based in United States.

More context: the Copper (Supplement) compound page, all human trials.