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Vitamin D and omega-3 polyunsaturated fatty acid supplementation in athletes with exercise-induced bronchoconstriction: a pilot study.

Plain-language guide to PMID 25864870 (2015): single-blind controlled clinical trial of Vitamin D, K2, Magnesium and Zinc.

Key Facts

PMID
25864870
Journal
Expert review of respiratory medicine
Year
2015
Study type
Controlled Clinical Trial
Authors
Price OJ et al. (5 authors)
DOI
10.1586/17476348.2015.1036032

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this controlled clinical trial publication.

The aim of this pilot study was to determine the combined effect of vitamin D and omega-3 polyunsaturated fatty acid (PUFA) supplementation on airway function and inflammation in recreational athletes with exercise-induced bronchoconstriction (EIB).

Venous blood was collected at the beginning of each trial to determine vitamin D status.

Who Took Part

The age groups tagged for this paper are young adults, adults and middle-aged adults, both men and women.

All subjects attended the laboratory on three occasions.

How the Study Was Run

The researchers set it up as a single-blind, placebo-controlled and pilot study.

Only one side, usually the participants, was kept unaware of whether Vitamin D, K2, Magnesium and Zinc was given.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.

Ten recreational athletes with EIB participated in a single-blind, placebo-controlled trial over six consecutive weeks.

Spirometry was performed pre- and post-eucapnic voluntary hyperpnoea (EVH).

What Was Measured

PubMed files the paper under topics including Asthma, Exercise-Induced, Athletes, Bronchoconstriction, Dietary Supplements, Exercise, Fatty Acids, Omega-3 and Forced Expiratory Volume.

The authors tagged it with the keywords airway dysfunction, exercise-induced bronchoconstriction, inflammation, omega-3 polyunsaturated fatty acids and vitamin D.

What This Means in Plain Language

The paper is a single-blind, placebo-controlled and pilot study of Vitamin D, K2, Magnesium and Zinc.

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2015 (Expert review of respiratory medicine), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.