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Effect of Vitamin D Supplementation on Glycemic Control in Patients With Type 2 Diabetes (SUNNY Trial): A Randomized Placebo-Controlled Trial.

Plain-language guide to PMID 25972575 (2015): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 275 patients.

Key Facts

PMID
25972575
Journal
Diabetes care
Year
2015
Study type
Randomized Controlled Trial
Authors
Krul-Poel YH et al. (9 authors)
DOI
10.2337/dc15-0323

What This Study Did, in Plain Language

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

The purpose of their study was to evaluate the effect of vitamin D supplementation on glycemic control in patients with type 2 diabetes.

To assess the primary outcome of the study, change in HbA(1c), the researchers performed a linear regression analysis.

Who Took Part

The study group was 275 patients.

The age groups tagged for this paper are middle-aged adults and older adults, both men and women.

This randomized, double-blind, placebo-controlled trial was conducted in 275 adult patients with type 2 diabetes without insulin treatment.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

Some patients received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

PubMed files the paper under topics including Blood Glucose, Diabetes Mellitus, Type 2, Dietary Supplements, Hypoglycemic Agents and Vitamin D.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 275 patients.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2015 (Diabetes care), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.