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Parental oxytocin responses during skin-to-skin contact in pre-term infants
Plain-language guide to PMID 25988992 (2015): crossover randomized controlled trial study of Oxytocin.
Key Facts
- PMID
- 25988992
- Journal
- Early human development
- Year
- 2015
- Study type
- Randomized Controlled Trial
- Authors
- Cong X et al. (8 authors)
- DOI
- 10.1016/j.earlhumdev.2015.04.012
What This Study Did, in Plain Language
What Was Tested
Researchers studied Oxytocin in this randomized controlled trial publication.
The purpose of the study was to examine oxytocin mechanism in modulating parental stress and anxiety during M-SSC and P-SSC (paternal SSC) with their pre-term infants.
Who Took Part
The age groups tagged for this paper are adults, both men and women.
Twenty-eight stable pre-term infants and their parents (triads) were recruited in a 2-day cross-over study and 26 mothers and 19 fathers completed the study protocol.
How the Study Was Run
The researchers set it up as a randomized and crossover study.
Because people in this Oxytocin study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Each person switched between Oxytocin and the comparison at some point, usually with a gap in between.
Each triad was randomly assigned to one of the two sequences: M-SSC was conducted on day-1 and P-SSC on day-2; and P-SSC on day-1 and M-SSC on day-2.
Parents' saliva samples for oxytocin and cortisol assays and visual analog anxiety levels were collected pre-SSC, 30-min during-SSC, and 30-min post-SSC.
What Was Measured
PubMed files the paper under topics including Anxiety, Fathers, Hydrocortisone, Infant, Premature, Kangaroo-Mother Care Method, Mothers and Oxytocin.
Author keywords: Cortisol, Maternal skin-to-skin contact, Paternal skin-to-skin contact and Pre-term infants.
What This Means in Plain Language
The paper is a randomized and crossover study of Oxytocin.
Its findings take up roughly 8 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2015 (Early human development), a journal based in Ireland.
More context: the Oxytocin compound page, all human trials.
Our Notes on the Compound
Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.