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Focused parathyroidectomy without intra-operative parathyroid hormone monitoring for primary hyperparathyroidism: results in a low-volume hospital
Plain-language guide to PMID 26072937 (2015): clinical study of Parathyroid Hormone (PTH 1-84) in 2012, patients, hyperparathyroidism.
Key Facts
- PMID
- 26072937
- Journal
- The Journal of laryngology and otology
- Year
- 2015
- Study type
- Clinical Study
- Authors
- Chow TL et al. (3 authors)
- DOI
- 10.1017/S0022215115000651
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Parathyroid Hormone (PTH 1-84) in the context of hyperparathyroidism, published as a clinical study.
The role of routine intra-operative parathyroid hormone monitoring for sporadic primary hyperparathyroidism is contentious.
Satisfactory results can be achieved in high-volume centres.
Who Took Part
According to the abstract, 2012, patients were involved.
By PubMed's age tags, the people studied were adults, middle-aged adults and older adults, both men and women.
From November 2002 to October 2012, 105 patients with clinically sporadic primary hyperparathyroidism underwent focused parathyroidectomy without intra-operative parathyroid hormone monitoring.
How the Study Was Run
A retrospective, non-comparative study was conducted.
Single adenoma was localised on pre-operative ultrasonography or sestamibi scan.
What Was Measured
The role of routine intra-operative parathyroid hormone monitoring for sporadic primary hyperparathyroidism is contentious.
The subject headings attached to it are Adenoma, Anesthesia, General, Anesthesia, Local, Hong Kong, Hospitals, Low-Volume, Hyperparathyroidism, Primary and Hypocalcemia.
The authors tagged it with the keywords Intraoperative Monitoring, Outcome Study, Parathyroid Hormone, Parathyroidectomy and Primary Hyperparathyroidism.
What This Means in Plain Language
This is a clinical study of Parathyroid Hormone (PTH 1-84) in 2012, patients in people with hyperparathyroidism.
With several hundred people or more, it is a fairly large study for this kind of research.
The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2015 (The Journal of laryngology and otology), a journal based in England.
More context: the Parathyroid Hormone (PTH 1-84) compound page, Hyperparathyroidism research.
Our Notes on the Compound
Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.