Growth, development, puberty and adult height before and during treatment in children with congenital isolated growth hormone deficiency.

What Was Tested

The paper reports a study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRH (Growth Hormone-Releasing Hormone), published as a clinical study.

To describe the growth, development and puberty in children with congenital IGHD before and during hGH treatment.

Who Took Part

The study group was 41 patients.

By PubMed's age tags, the people studied were infants, young children, children, teenagers and young adults, both men and women.

Patients with cIGHD treated by hGH between the years 1958-1992.

All patients were diagnosed, treated and followed in their clinic.

How the Study Was Run

Data were found in 37/41 patients (21 m, 16 f). 34 had hGH-1A deletions, 7 GHRH-R mutations.

Patients, referred after age 25, were excluded.

What Was Measured

The subject headings attached to it are Body Height, Body Mass Index, Child Development, Cohort Studies, Dwarfism, Pituitary, Hormone Replacement Therapy and Human Growth Hormone.

Author keywords: Adiposity, Age at first ejaculation, BMI, Congenital IGHD, GHRH-R mutations and Menarche.

What This Means in Plain Language

This is a clinical study of Exogenous HGH, sermorelin & older GHRPs (why they're passed over) and GHRH (Growth Hormone-Releasing Hormone) in 41 patients.

Its findings take up roughly 16 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2015 (Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society), a journal based in Scotland.

More context: the Exogenous HGH, sermorelin & older GHRPs (why they're passed over) compound page and the GHRH (Growth Hormone-Releasing Hormone) compound page, all human trials.