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Vitamin D Supplementation Does Not Improve the Severity or the Resolution of Ultraviolet B-Induced Acute Erythema.

Plain-language guide to PMID 26111868 (2015): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 50 volunteers.

Key Facts

PMID
26111868
Journal
Dermatology (Basel, Switzerland)
Year
2015
Study type
Randomized Controlled Trial
Authors
Libon F et al. (4 authors)
DOI
10.1159/000430983

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

To study the effect of oral vitamin D on UVB-induced erythema and its resolution in fair-skinned subjects.

Why It Was Studied

Whether vitamin D supplementation alleviates the severity of ultraviolet B (UVB)-induced erythema and/or facilitates its resolution remains undetermined.

Who Took Part

The abstract describes 50 volunteers taking part.

The age groups tagged for this paper are young adults, both men and women.

How the Study Was Run

In design terms this was a randomized, placebo-controlled and pilot study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The comparison arm used a placebo, so changes seen with Vitamin D, K2, Magnesium and Zinc could be set against what happens without it.

It is described as a pilot, a small early test of whether a larger Vitamin D, K2, Magnesium and Zinc study would be practical.

Resolution of erythema in both groups was assessed by chromametry 24, 48, and 72 h after vitamin D administration.

What Was Measured

Topics PubMed links to this paper include Dietary Supplements, Erythema, Pilot Projects, Seasons, Ultraviolet Rays, Vitamin D and Vitamins.

What This Means in Plain Language

The paper is a randomized, placebo-controlled and pilot study of Vitamin D, K2, Magnesium and Zinc in 50 volunteers.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2015 (Dermatology (Basel, Switzerland)), a journal based in Switzerland.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.