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Does oxytocin affect mind-reading? A replication study
Plain-language guide to PMID 26142239 (2015): double-blind randomized controlled trial study of Oxytocin.
Key Facts
- PMID
- 26142239
- Journal
- Psychoneuroendocrinology
- Year
- 2015
- Study type
- Randomized Controlled Trial
- Authors
- Radke S et al. (2 authors)
- DOI
- 10.1016/j.psyneuen.2015.06.006
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial paper looks at Oxytocin.
(2007), the aim of the current study was to replicate and extend previous findings by thoroughly investigating the impact of oxytocin administration on RMET performance.
Why It Was Studied
Following the original design of Domes et al.
The researchers tested for potential moderation effects involving item difficulty, valence, intensity, sex of poser as well as individual differences in trait empathy measured with the Empathy Quotient (EQ) for a general score and the Interpersonal Reactivity Index (IRI) for a multidimensional assessment of cognitive and emotional empathy.
Who Took Part
PubMed indexes the participants as young adults and adults, both men and women.
How the Study Was Run
The researchers set it up as a randomized, double-blind and placebo-controlled study.
The participants were allocated by chance, so the Oxytocin group and the comparison group should start out alike.
Blinding on both sides kept the participants and researchers unaware of who received Oxytocin.
A placebo (an inactive look-alike) gave the Oxytocin group a baseline to be compared against.
What Was Measured
The researchers tested for potential moderation effects involving item difficulty, valence, intensity, sex of poser as well as individual differences in trait empathy measured with the Empathy Quotient (EQ) for a general score and the Interpersonal Reactivity Index (IRI) for a multidimensional assessment of cognitive and emotional empathy.
The subject headings attached to it are Empathy, Eye, Facial Expression, Interpersonal Relations, Neuropsychological Tests, Oxytocin and Psychomotor Performance.
The authors tagged it with the keywords Mind-reading, RMET, Replication and Social cognition.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Oxytocin.
The publication is from 2015 (Psychoneuroendocrinology), a journal based in England.
More context: the Oxytocin compound page, all human trials.
Our Notes on the Compound
Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.