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Recurrence rate of ovarian endometriosis in patients treated with laparoscopic surgery and postoperative suppressive therapy

Plain-language guide to PMID 26152006 (2015): clinical trial study of Triptorelin, endometriosis.

Key Facts

PMID
26152006
Journal
Clinical and experimental obstetrics & gynecology
Year
2015
Study type
Clinical Trial
Authors
Dimitrijevic D et al. (6 authors)

What This Study Did, in Plain Language

What Was Tested

This clinical trial paper looks at Triptorelin in the context of endometriosis.

The research objective was to determine the percentage of occurrence of relapses in patients operated for endometriosis of the ovary in relation to the stage of the disease and the type of performed operation, and which were receiving suppressive therapy with gonadotropin-releasing hormone (GnRH) analogues after the surgery compared to those who were not receiving suppressive therapy after the operation.

Why It Was Studied

The testing represented a prospective study that was performed at the Gynaecology and Obstetrics Clinic "Narodni Front" in Belgrade during a two-year period.

The study encompassed female patients with ovarian endometrioma operated with laparoscopic surgery.

Who Took Part

By PubMed's age tags, the people studied were young adults, adults and middle-aged adults, women only.

In all patients ultrasound checks were done every month during the first six months after surgery, and then every three months for the next six months.

In all patients in whom the recurrence, i.e. endometrioma on the ovary larger than three cm was revealed postoperatively by ultrasound, the laparoscopic removal of the endometrioma was performed again as well as the histopathological examination of the material.

How the Study Was Run

The recurrence of endometriosis on the ovary of the test and control groups was monitored during the first year after surgery.

What Was Measured

The testing represented a prospective study that was performed at the Gynaecology and Obstetrics Clinic "Narodni Front" in Belgrade during a two-year period.

PubMed files the paper under topics including Endometriosis, Gonadotropin-Releasing Hormone, Goserelin, Gynecologic Surgical Procedures, Laparoscopy, Ovarian Diseases and Ovary.

What This Means in Plain Language

This is a clinical trial of Triptorelin in people with endometriosis.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2015 (Clinical and experimental obstetrics & gynecology), a journal based in Singapore.

More context: the Triptorelin compound page, Endometriosis research.

Our Notes on the Compound

Triptorelin: A 10-amino-acid GnRH analog (Trelstar, Decapeptyl, Triptodur) used in prostate cancer, early puberty and fertility protocols.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.