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A High Omega-3 Fatty Acid Multinutrient Supplement Benefits Cognition and Mobility in Older Women: A Randomized, Double-blind, Placebo-controlled Pilot Study.

Plain-language guide to PMID 26265727 (2016): double-blind randomized controlled trial of Fatty Acids, Omega-3.

Key Facts

PMID
26265727
Journal
The journals of gerontology. Series A, Biological sciences and medical sciences
Year
2016
Study type
Randomized Controlled Trial
Authors
Strike SC et al. (4 authors)
DOI
10.1093/gerona/glv109

What This Study Did, in Plain Language

What Was Tested

Researchers studied Fatty Acids, Omega-3 in this randomized controlled trial publication.

Who Took Part

PubMed indexes the participants as middle-aged adults, older adults and people over 80, women only.

The effects of a multinutrient supplement on mobility and cognition were assessed in postmenopausal women (60-84 years).

How the Study Was Run

In design terms this was a randomized, double-blind, placebo-controlled and pilot study.

Random assignment meant chance, not the researchers, decided who got Fatty Acids, Omega-3 and who got the comparison, which limits bias.

Blinding on both sides kept the participants and researchers unaware of who received Fatty Acids, Omega-3.

A placebo (an inactive look-alike) gave the Fatty Acids, Omega-3 group a baseline to be compared against.

It is described as a pilot, a small early test of whether a larger Fatty Acids, Omega-3 study would be practical.

Mobility was assessed by VICON 9 motion capture camera system synchronized with Kistler force plates, cognitive performance by computerized cognitive function tests, and blood fatty acid levels by pin-prick analysis.

What Was Measured

Topics PubMed links to this paper include Cognition Disorders, Dietary Supplements, Fatty Acids, Omega-3, Fish Oils, Frail Elderly, Gait Disorders, Neurologic and Pilot Projects.

The authors tagged it with the keywords Aging, B vitamins, Docosahexaenoic acid and Memory.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Fatty Acids, Omega-3.

The abstract goes on to report its results in about 3 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (The journals of gerontology. Series A, Biological sciences and medical sciences), a journal based in United States.

More context: all human trials.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.