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Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study.

Plain-language guide to PMID 26275945 (2016): review of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

Key Facts

PMID
26275945
Journal
The Journal of steroid biochemistry and molecular biology
Year
2016
Study type
Review
Authors
Brouwer-Brolsma EM et al. (16 authors)
DOI
10.1016/j.jsbmb.2015.08.008

What This Paper Covers, in Plain Language

What It Covers

Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in this review publication.

The prevalence of vitamin D deficiency among seniors is high.

Whereas sun exposure, vitamin D intake, genes, demographics, and lifestyle have been identified as being important determinants of vitamin D status, the impact of these factors is expected to differ across populations.

Who the Included Studies Covered

The age groups tagged for this paper are older adults and people over 80, both men and women.

Serum 25-hydroxyvitamin D (25(OH)D) was measured in 2857 adults aged ≥65 years.

How the Review Was Done

Sun exposure was assessed with a structured questionnaire (n=1012), vitamin D intake using a Food Frequency Questionnaire (n=596), and data on genetic variation that may affect 25(OH)D status was obtained for 4 genes, DHCR7 (rs12785878), CYP2R1 (rs10741657), GC (rs2282679), and CYP24A1 (rs6013897) (n=2530).

What Was Measured

PubMed files the paper under topics including Cholestanetriol 26-Monooxygenase, Cross-Sectional Studies, Cytochrome P450 Family 2, Dietary Supplements, Oxidoreductases Acting on CH-CH Group Donors, Polymorphism, Single Nucleotide and Seasons.

Author keywords: Serum 25-hydroxyvitamin D, Sunlight, Vitamin D intake, Vitamin D related genetic variation and Vitamin D supplement.

What This Means in Plain Language

This is a review of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (The Journal of steroid biochemistry and molecular biology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.

Our Notes on the Compounds

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.