Prevalence and predictors of vitamin D deficiency based on maternal mid-gestation and neonatal cord bloods: The Generation R Study.

What It Covers

This review looks at Vitamin D, K2, Magnesium and Zinc.

Population-based studies have confirmed that the prevalence of vitamin D deficiency is substantial in many societies, and is of particular concern in pregnant women.

To date, studies of vitamin D deficiency during pregnancy have focused on measurements at one or two time points in isolation.

Who the Included Studies Covered

By PubMed's age tags, the people studied were young adults and adults, women only.

How the Review Was Done

This study was embedded in the Generation R Study, a population-based prospective cohort from fetal life onwards in Rotterdam, The Netherlands.

Using a highly sensitive tandem mass spectroscopy-based assay, the researchers measured 25OHD in 7256 midgestation samples (mean gestation 20.6 weeks) and 5023 neonatal cord blood samples (mean gestation 40.0 weeks).

The researchers also derived a measure of vitamin D deficiency based on the two time points in order to explore persistent vitamin D deficiency in mother-infant pairs.

What Was Measured

To date, studies of vitamin D deficiency during pregnancy have focused on measurements at one or two time points in isolation.

PubMed files the paper under topics including Fetal Blood, Prevalence, Seasons, Vitamin D and Vitamin D Deficiency.

The authors tagged it with the keywords 25 Hydroxyvitamin D, Cord blood, Epidemiology, Prenatal and Risk factors.

What This Means in Plain Language

This is a review of Vitamin D, K2, Magnesium and Zinc.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (The Journal of steroid biochemistry and molecular biology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.