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Combination of motherwort injection and oxytocin for the prevention of postpartum hemorrhage after cesarean section
Plain-language guide to PMID 26414626 (2016): double-blind randomized controlled trial study of Oxytocin.
Key Facts
- PMID
- 26414626
- Journal
- The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
- Year
- 2016
- Study type
- Randomized Controlled Trial
- Authors
- Liu W et al. (4 authors)
- DOI
- 10.3109/14767058.2015.1090425
What This Study Did, in Plain Language
What Was Tested
This randomized controlled trial paper looks at Oxytocin.
Who Took Part
By PubMed's age tags, the people studied were adults, women only.
How the Study Was Run
The design is described as randomized and double-blind.
Random assignment meant chance, not the researchers, decided who got Oxytocin and who got the comparison, which limits bias.
As a double-blind Oxytocin study, the assignments were hidden from both participants and investigators until the end.
From March 2011 and February 2013, a randomized study was conducted on 165 primipara undergoing CS. 83 and 82 cases were placed into the combination of oxytocin and motherwort group and oxytocin group, respectively.
Blood loss was calculated and measured during three periods: from placental delivery to the end of CS, from the end of CS to 2 h postpartum and from 2 h postpartum to 24 h postpartum.
Vital signs were also measured.
What Was Measured
Topics PubMed links to this paper include Cesarean Section, Delivery, Obstetric, Leonurus, Oxytocics, Oxytocin and Postpartum Hemorrhage.
Author keywords: motherwort.
What This Means in Plain Language
The paper is a randomized and double-blind study of Oxytocin.
The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2016 (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians), a journal based in England.
More context: the Oxytocin compound page, all human trials.
Our Notes on the Compound
Oxytocin: A peptide hormone with established obstetric medical uses and a less settled role in research on behavior, sexual function and appetite.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.