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The effects of vitamin D plus calcium supplementation on metabolic profiles, biomarkers of inflammation, oxidative stress and pregnancy outcomes in pregnant women at risk for pre-eclampsia.
Plain-language guide to PMID 26467311 (2016): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 60 women.
Key Facts
- PMID
- 26467311
- Journal
- Journal of human nutrition and dietetics : the official journal of the British Dietetic Association
- Year
- 2016
- Study type
- Randomized Controlled Trial
- Authors
- Samimi M et al. (9 authors)
- DOI
- 10.1111/jhn.12339
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
The present study was designed to examine the effects of vitamin D plus calcium administration on metabolic profiles and pregnancy outcomes among women at risk for pre-eclampsia.
Fasting blood samples were taken at baseline and 12 weeks after intervention to determine related variables.
Who Took Part
The study group was 60 women.
The age groups tagged for this paper are teenagers, young adults and adults, women only.
Newborn anthropometric measurements were determined.
How the Study Was Run
The design is described as randomized, double-blind and placebo-controlled.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.
Some women received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.
What Was Measured
The subject headings attached to it are Biomarkers, Calcium Carbonate, Calcium, Dietary, Cholecalciferol, Dietary Supplements, Inflammation Mediators and Insulin Resistance.
Author keywords: pre-eclampsia, pregnancy outcomes, supplementation and vitamin D.
What This Means in Plain Language
The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 60 women.
The abstract goes on to report its results in about 4 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2016 (Journal of human nutrition and dietetics : the official journal of the British Dietetic Association), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.