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Late-onset hypogonadism: the advantages of treatment with human chorionic gonadotropin rather than testosterone

Plain-language guide to PMID 26488941 (2016): randomized controlled trial study of hCG (human chorionic gonadotropin) in 40 patients.

Key Facts

PMID
26488941
Journal
The aging male : the official journal of the International Society for the Study of the Aging Male
Year
2016
Study type
Randomized Controlled Trial
Authors
La Vignera S et al. (6 authors)
DOI
10.3109/13685538.2015.1092021

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial paper looks at hCG (human chorionic gonadotropin).

Finally, another important aspect of LOH is represented by the frequency of secondary infertility due to age or to traditional HRT.

This study evaluated 40 LOH patients treated for 6 months with extractive HCG (n = 10 patients) and three different formulations of T: transdermal (n = 10 patients), undecaonate (n = 10 patients) and enantate (n = 10 patients).

Who Took Part

The abstract describes 40 patients taking part.

The age groups tagged for this paper are middle-aged adults, men only.

How the Study Was Run

The design is described as randomized.

Because people in this hCG (human chorionic gonadotropin) study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

The timeline in the abstract includes 6 months.

What Was Measured

Finally, another important aspect of LOH is represented by the frequency of secondary infertility due to age or to traditional HRT.

This study evaluated 40 LOH patients treated for 6 months with extractive HCG (n = 10 patients) and three different formulations of T: transdermal (n = 10 patients), undecaonate (n = 10 patients) and enantate (n = 10 patients).

The subject headings attached to it are Administration, Cutaneous, Chorionic Gonadotropin, Hematocrit, Hormone Replacement Therapy, Hypogonadism, Prostate and Prostate-Specific Antigen.

The authors tagged it with the keywords Human chorionic gonadotropin, late onset hypogonadism and testosterone.

What This Means in Plain Language

The paper is a randomized study of hCG (human chorionic gonadotropin) in 40 patients over 6 months.

The publication is from 2016 (The aging male : the official journal of the International Society for the Study of the Aging Male), a journal based in England.

More context: the hCG (human chorionic gonadotropin) compound page, all human trials.

Our Notes on the Compound

hCG (human chorionic gonadotropin): An LH analog that drives Leydig-cell testosterone production.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.