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Early pregnancy vitamin D status and risk for adverse maternal and infant outcomes in a bi-ethnic cohort: the Behaviors Affecting Baby and You (B.A.B.Y.) Study.
Plain-language guide to PMID 26507186 (2015): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 237 participants.
Key Facts
- PMID
- 26507186
- Journal
- The British journal of nutrition
- Year
- 2015
- Study type
- Randomized Controlled Trial
- Authors
- Nobles CJ et al. (3 authors)
- DOI
- 10.1017/S0007114515003980
What This Study Did, in Plain Language
What Was Tested
Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.
Vitamin D deficiency is common during pregnancy and higher in Hispanic as compared with non-Hispanic white women.
However, the association between vitamin D deficiency and adverse pregnancy outcomes remains unclear and may vary across ethnic groups, in part because of genetic variation in the metabolism of vitamin D.
Who Took Part
According to the abstract, 237 participants were involved.
By PubMed's age tags, the people studied were teenagers, young adults and adults, women only.
How the Study Was Run
The researchers set it up as a randomized study.
Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.
Baseline serum 25-hydroxyvitamin D (25(OH)D) was measured at 15·2 (sd 4·7) weeks' gestation.
What Was Measured
However, the association between vitamin D deficiency and adverse pregnancy outcomes remains unclear and may vary across ethnic groups, in part because of genetic variation in the metabolism of vitamin D.
Information on adverse pregnancy outcomes was abstracted from medical records.
The subject headings attached to it are Cohort Studies, Ethnicity, Hispanic or Latino, Massachusetts, Pregnancy Outcome and Vitamin D.
The authors tagged it with the keywords 25(OH)D 25-hydroxyvitamin D, B.A.B.Y. Behaviors Affecting Baby and You, Epidemiology, GDM gestational diabetes mellitus, Gestational diabetes and LGA large for gestational age.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 237 participants.
The publication is from 2015 (The British journal of nutrition), a journal based in England.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.