Vitamin D3 supplementation does not modify cardiovascular risk profile of adults with inadequate vitamin D status.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Who Took Part

The study group was 105 subjects.

PubMed indexes the participants as adults, middle-aged adults and older adults, both men and women.

A total of 105 apparently healthy subjects (male and female, 20-71 years old) were included.

Subjects were randomly allocated to two groups.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

The subjects were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

The study was conducted in Halle (Saale), Germany (51o northern latitude) as a placebo-controlled, double-blinded, randomised trial (from January to April).

Outcome measures included blood pressure, heart rate, concentrations of renin, aldosterone, serum lipids and vascular calcification markers, and haematologic variables such as pro-inflammatory monocytes.

What Was Measured

PubMed files the paper under topics including Biomarkers, Blood Pressure, Calcifediol, Cardiovascular Diseases, Cholecalciferol, Dietary Supplements and Germany.

Author keywords: Adults, Cardiovascular risk, Monocyte subsets, Supplementation and Vitamin D3.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 105 subjects.

Its findings take up roughly 3 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2017 (European journal of nutrition), a journal based in Germany.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.