Impact of weekly iron folic acid supplementation with and without vitamin B12 on anaemic adolescent girls: a randomised clinical trial

What Was Tested

Researchers studied Cyanocobalamin (Vitamin B12) in this randomized controlled trial publication.

Who Took Part

According to the abstract, 373 subjects were involved.

The age groups tagged for this paper are children and teenagers, women only.

A total of 373 subjects completed 26 weeks of supplementation successfully.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

The subjects were allocated by chance, so the Cyanocobalamin (Vitamin B12) group and the comparison group should start out alike.

Blinding on both sides kept the subjects and researchers unaware of who received Cyanocobalamin (Vitamin B12).

The comparison arm used a placebo, so changes seen with Cyanocobalamin (Vitamin B12) could be set against what happens without it.

Community-based randomized controlled trial was carried out in Kirti Nagar slums of West Delhi.

Haemoglobin, serum ferritin, folic acid and vitamin B12 levels were assessed at baseline and after intervention.

What Was Measured

PubMed files the paper under topics including Anemia, Iron-Deficiency, Dietary Supplements, Ferritins, Folic Acid, Hemoglobins, India and Iron.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Cyanocobalamin (Vitamin B12) in 373 subjects.

With several hundred people or more, it is a fairly large study for this kind of research.

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2016 (European journal of clinical nutrition), a journal based in England.

More context: the Cyanocobalamin (Vitamin B12) compound page, all human trials.