The effects of sequential use of oxytocin and sublingual nitroglycerin in the cases of retained placenta

What Was Tested

The paper reports a study of Oxytocin, published as a randomized controlled trial.

To evaluate the effects of adding sublingual nitroglycerin to oxytocin, for delivery of retained placenta after vaginal delivery.

Who Took Part

By PubMed's age tags, the people studied were young adults and adults, women only.

The study was performed as a placebo controlled clinical trial on women who did not finish delivering placenta after 30 min of active management of the third stage of labor.

How the Study Was Run

The design is described as randomized and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Oxytocin and who got the comparison, which limits bias.

A placebo (an inactive look-alike) gave the Oxytocin group a baseline to be compared against.

What Was Measured

PubMed files the paper under topics including Administration, Sublingual, Nitroglycerin, Oxytocics, Oxytocin, Placenta, Retained and Vasodilator Agents.

Author keywords: Manual removal of placenta, pregnancy and delivery, retained placenta and third stage of labor.

What This Means in Plain Language

The paper is a randomized and placebo-controlled study of Oxytocin.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2016 (The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians), a journal based in England.

More context: the Oxytocin compound page, all human trials.