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Response of Vitamin D Concentration to Vitamin D3 Administration in Older Adults without Sun Exposure: A Randomized Double-Blind Trial.

Plain-language guide to PMID 26782853 (2016): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 81 women.

Key Facts

PMID
26782853
Journal
Journal of the American Geriatrics Society
Year
2016
Study type
Randomized Controlled Trial
Authors
Schwartz JB et al. (3 authors)
DOI
10.1111/jgs.13774

What This Study Did, in Plain Language

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Who Took Part

According to the abstract, 81 women were involved.

By PubMed's age tags, the people studied were older adults and people over 80, both men and women.

Of 81 women (n=51) and men (n=30) (mean age 87.4±8) enrolled, 72 completed the study.

How the Study Was Run

The researchers set it up as a randomized and double-blind study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Blinding on both sides kept the women and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Free 25(OH)D and intact parathyroid hormone (iPTH) were also analyzed.

Safety monitoring of calcium and estimated glomerular filtration rate was performed, and adherence and clinical status were measured.

What Was Measured

The subject headings attached to it are Cholecalciferol, Sunlight, Tandem Mass Spectrometry, Vitamin D, Vitamin D Deficiency and Vitamins.

Author keywords: 25(OH)D, elderly and iPTH.

What This Means in Plain Language

The paper is a randomized and double-blind study of Vitamin D, K2, Magnesium and Zinc in 81 women.

Its findings take up roughly 9 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2016 (Journal of the American Geriatrics Society), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.

Our Notes on the Compound

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.