The Effects of Oral Vitamin D Supplement on Atopic Dermatitis: A Clinical Trial with Staphylococcus aureus Colonization Determination.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc and Copper (Supplement) in this randomized controlled trial publication.

To determine the effects of oral vitamin D supplements on clinical impact including Staphylococcus aureus skin colonization evaluation in atopic dermatitis patients.

Who Took Part

By PubMed's age tags, the people studied were infants, young children, children and teenagers, both men and women.

Twenty-four atopic dermatitis patients were included in this double-blind, placebo-controlled study.

They were randomly assigned into 2 groups for oral 2,000 IUs/day of vitamin D, supplement and placebo.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Neither the participants nor the staff measuring them knew who was on Vitamin D, K2, Magnesium and Zinc, so expectations could not easily colour the readings.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

The lesional swab culture for S. aureus was done at week 0, 2 and 4.

Clinical outcomes were assessed by SCORAD score, mexameter for erythema index and konometer for conductance were done at week 0, 2 and 4.

Serum vitamin D levels were also determined at week 0 and 4.

What Was Measured

Topics PubMed links to this paper include Dermatitis, Atopic, Dietary Supplements, Skin, Staphylococcal Infections, Staphylococcus aureus, Vitamin D and Vitamins.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).

Results are reported in around 4 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2015 (Journal of the Medical Association of Thailand = Chotmaihet thangphaet), a journal based in Thailand.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.