Effect of zinc and multivitamin supplementation on the growth of Tanzanian children aged 6-84 wk: a randomized, placebo-controlled, double-blind trial.

What Was Tested

This randomized controlled trial looks at Vitamin D, K2, Magnesium and Zinc.

Likelihood ratio tests were used to compare the effect of supplements on growth trajectories.

Who Took Part

According to the abstract, 2400 infants were involved.

By PubMed's age tags, the people studied were young children, children, young adults and adults, both men and women.

How the Study Was Run

In design terms this was a randomized, double-blind and placebo-controlled study.

Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

Some infants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

Mixed-effects models with restricted cubic splines for the mean change in anthropometric z scores were fit for each group.

What Was Measured

Topics PubMed links to this paper include Body Height, Dietary Supplements, Growth, Growth Disorders, Tanzania, Thinness and Trace Elements.

Author keywords: infancy, multiple micronutrients, supplementation and zinc.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 2400 infants.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 8 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.