← Human Trials & Peer-Reviewed Studies
Effects of vitamin D on blood pressure in patients with type 2 diabetes mellitus.
Plain-language guide to PMID 26902507 (2016): meta-analysis of Vitamin D, K2, Magnesium and Zinc, low blood pressure and orthostatic hypotension.
Key Facts
- PMID
- 26902507
- Journal
- International journal of clinical pharmacology and therapeutics
- Year
- 2016
- Study type
- Meta-Analysis
- Authors
- Lee KJ et al. (2 authors)
- DOI
- 10.5414/CP202493
What This Paper Covers, in Plain Language
What It Covers
The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of low blood pressure and orthostatic hypotension, published as a meta-analysis.
The purpose of this meta-analysis was to evaluate the effects of the vitamin D supplementation on blood pressure in patients with type 2 diabetes.
Who the Included Studies Covered
Eligible studies were identified via a literature search of the MEDLINE (PubMed), EMBASE, and Cochrane Library databases through to May 25, 2015.
The endpoint of the analysis was the change in blood pressure due to vitamin D treatment in patients with type 2 diabetes.
How the Review Was Done
A meta-analysis of published randomized controlled trials was conducted.
These changes were calculated as the difference between the baseline and final measurements performed in each study.
A fixed-effects model was used to calculate the combined effect estimates; in the presence of heterogeneity, a random-effects model was used.
What Was Measured
PubMed files the paper under topics including Blood Pressure, Diabetes Mellitus, Type 2, Dietary Supplements and Vitamin D.
What This Means in Plain Language
This is a meta-analysis of Vitamin D, K2, Magnesium and Zinc in people with low blood pressure and orthostatic hypotension.
The abstract goes on to report its results in about 7 sentences; this page does not restate them, so read the paper for the findings and their limits.
The publication is from 2016 (International journal of clinical pharmacology and therapeutics), a journal based in Germany.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, Low blood pressure and orthostatic hypotension research.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
- Low blood pressure and orthostatic hypotension research
- Vitamin D, K2, Magnesium and Zinc in the library
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.