Vitamin D levels and atopic eczema in infancy and early childhood in Norway: a cohort study.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in the context of eczema in this clinical trial publication.

Who Took Part

The abstract describes 596 children taking part.

The age groups tagged for this paper are infants and young children.

Infants, recruited to a clinical trial on acute bronchiolitis (n = 404) and from the general population (n = 240), were examined at 1-13 months (first visit) and at 2 years of age (second visit).

AE was diagnosed clinically, based on well-established criteria.

How the Study Was Run

Caregivers were interviewed using a structured questionnaire.

Disease severity was assessed using the SCORing Atopic Dermatitis index.

Blood samples were taken for vitD measurements, using liquid chromatography-tandem mass spectrometry and for common filaggrin mutation analyses.

Complete data on AE and vitD were available in 596 and 449 children at the first and second visit, respectively.

What Was Measured

PubMed files the paper under topics including 25-Hydroxyvitamin D 2, Calcifediol, Cross-Sectional Studies, Dermatitis, Atopic, Filaggrin Proteins, Intermediate Filament Proteins and Mutation.

What This Means in Plain Language

This is a clinical trial of Vitamin D, K2, Magnesium and Zinc in 596 children in people with eczema.

With several hundred people or more, it is a fairly large study for this kind of research.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (The British journal of dermatology), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Eczema research.