The effects of a fat loss supplement on resting metabolic rate and hemodynamic variables in resistance trained males: a randomized, double-blind, placebo-controlled, cross-over trial.

What Was Tested

Researchers studied the intervention named in the title in this randomized controlled trial publication.

The purpose of this study was to examine the effects of a commercially available thermogenic fat loss supplement on RMR and hemodynamic variables in healthy, resistance trained males.

Who Took Part

PubMed indexes the participants as adults, men only.

Ten resistance-trained male participants (29 ± 9 years; 178 ± 4 cm; 85.7 ± 11 kg, and BMI = 26.8 ± 3.7) volunteered to participate in this randomized, double-blind, placebo controlled cross-over study.

Participants underwent two testing sessions separated by at least 24 h.

How the Study Was Run

In design terms this was a randomized, double-blind, placebo-controlled and crossover study.

Random assignment meant chance, not the researchers, decided who got the intervention named in the title and who got the comparison, which limits bias.

As a double-blind study, the assignments were hidden from both participants and investigators until the end.

Some participants received a placebo instead, giving a reference point.

Each person switched between the intervention named in the title and the comparison at some point, usually with a gap in between.

On their first visit, participants arrived to the laboratory after an overnight fast and a 24-h avoidance of exercise, and underwent a baseline RMR, HR, and BP assessment.

Next, each participant ingested a thermogenic fat loss supplement (TFLS) or a placebo (PLA) and repeated the RMR, HR, and BP assessments at 60, 120, and 180 min post-ingestion.

During the second visit the alternative supplement was ingested and the assessments were repeated in the exact same manner.

Data were analyzed via a 2-factor [2x4] within-subjects repeated measures analysis of variance (ANOVA).

Post-hoc tests were analyzed via paired samples t-tests.

What Was Measured

Topics PubMed links to this paper include Basal Metabolism, Blood Pressure, Dietary Supplements, Energy Metabolism, Heart Rate, Hemodynamics and Oxygen Consumption.

The authors tagged it with the keywords Male physique enhancement, Sports nutrition and Weight loss fat loss.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study.

Results are reported in around 10 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2016 (Journal of the International Society of Sports Nutrition), a journal based in United States.

More context: all human trials.