Long-term magnesium supplementation improves arterial stiffness in overweight and obese adults: results of a randomized, double-blind, placebo-controlled intervention trial.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

The objective was to evaluate the effects of long-term magnesium supplementation on arterial stiffness.

Why It Was Studied

However, intervention trials of magnesium supplementation on blood pressure and conventional cardiometabolic risk markers are inconsistent.

Who Took Part

According to the abstract, 30 men were involved.

The age groups tagged for this paper are middle-aged adults and older adults, both men and women.

Twenty-four-hour urine collections and 24-h ambulatory blood pressure assessments were performed at the start and end of the study.

How the Study Was Run

The researchers set it up as a randomized, double-blind and placebo-controlled study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

Blinding on both sides kept the men and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Some men received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

The researchers performed a 24-wk, randomized, double-blind, placebo-controlled intervention study.

What Was Measured

PubMed files the paper under topics including Biomarkers, Blood Pressure, Blood Pressure Monitoring, Ambulatory, Body Mass Index, C-Reactive Protein, Creatinine and Dietary Supplements.

Author keywords: arterial stiffness, intervention study, magnesium and pulse wave velocity.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc in 30 men.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2016 (The American journal of clinical nutrition), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.