Mean Platelet Volume, Vitamin D and C Reactive Protein Levels in Normal Weight Children with Primary Snoring and Obstructive Sleep Apnea Syndrome.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of sleep apnea (obstructive), published as a clinical trial.

In this perspective, in a group of children affected by SDB, their aim was to investigate MPV, vitamin D and C Reactive Protein (CRP) levels, which had been previously evaluated separately in different studies focused only on Obstructive Sleep Apnea Syndrome (OSAS).

Why It Was Studied

Studies on Mean Platelet Volume (MPV) in children with Sleep Disordered Breathing (SDB) report conflicting results and the hypothesis of an intermittent hypoxemia leading to a systemic inflammation is reaching consensus.

Vitamin D exerts anti-inflammatory properties and its deficiency has been supposed to play a role in sleep disorders.

Who Took Part

The abstract describes 137 children taking part.

PubMed indexes the participants as children, both men and women.

The researchers enrolled 137 children: 70 healthy controls (HC), 67 affected by SDB undergoing a polysomnographic evaluation, 22 with a diagnosis of PS and 45 with a diagnosis of OSAS.

All patients underwent routine biochemical evaluations including blood cell counts, CRP and vitamin D.

What Was Measured

The subject headings attached to it are C-Reactive Protein, Mean Platelet Volume, Sleep Apnea, Obstructive, Snoring, Syndrome and Vitamin D.

What This Means in Plain Language

This is a clinical trial of Vitamin D, K2, Magnesium and Zinc in 137 children in people with sleep apnea (obstructive).

Results are reported in around 6 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2016 (PloS one), a journal based in United States.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, Sleep apnea (obstructive) research.