Vitamin D supplementation during pregnancy and infancy reduces aeroallergen sensitization: a randomized controlled trial.

What Was Tested

Researchers studied Vitamin D, K2, Magnesium and Zinc in this randomized controlled trial publication.

Vitamin D has immune-modulating effects.

Who Took Part

By PubMed's age tags, the people studied were infants, both men and women.

When the children were 18 months old, the researchers measured serum-specific IgE antibodies and identified acute primary care visits described by the doctor to be due to a cold, otitis media, an upper respiratory infection, croup, asthma, bronchitis, bronchiolitis, a wheezy lower respiratory infection or fever and cough.

How the Study Was Run

The researchers set it up as a randomized, double-blind, placebo-controlled and parallel-group study.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

As a double-blind Vitamin D, K2, Magnesium and Zinc study, the assignments were hidden from both participants and investigators until the end.

A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.

Groups ran in parallel: each of the participants stayed in one arm throughout.

A randomized, double-blind, placebo-controlled parallel-group trial.

What Was Measured

The subject headings attached to it are Allergens, Comorbidity, Dietary Supplements, Hypersensitivity, Hypersensitivity, Immediate, Immunoglobulin E and Maternal Exposure.

Author keywords: Vitamin D, 25-hydroxyvitamin D, asthma, infant, pregnancy and supplementation.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc.

Its findings take up roughly 6 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2016 (Allergy), a journal based in Denmark.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.