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Associations between Vitamin D Status and Type 2 Diabetes Measures among Inuit in Greenland May Be Affected by Other Factors.
Plain-language guide to PMID 27073876 (2016): randomized controlled trial of Vitamin D, K2, Magnesium and Zinc in 330 individuals.
Key Facts
- PMID
- 27073876
- Journal
- PloS one
- Year
- 2016
- Study type
- Randomized Controlled Trial
- Authors
- Nielsen NO et al. (10 authors)
- DOI
- 10.1371/journal.pone.0152763
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.
Epidemiological studies have provided evidence of an association between vitamin D insufficiency and type 2 diabetes.
Who Took Part
The study group was 330 individuals.
By PubMed's age tags, the people studied were teenagers, young adults, adults and middle-aged adults, both men and women.
How the Study Was Run
The researchers set it up as a randomized study.
The individuals were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.
2877 Inuit (≥18 years) randomly selected for participation in the Inuit Health in Transition study were included.
Fasting- and 2hour plasma glucose and insulin, C-peptide and HbA1c were measured, and associations with serum 25(OH)D3 were analysed using linear and logistic regression.
A subsample of 330 individuals who also donated a blood sample in 1987, were furthermore included.
What Was Measured
Topics PubMed links to this paper include Blood Glucose, Diabetes Mellitus, Type 2, Glucose Intolerance, Glucose Tolerance Test, Greenland, Inuit and Prediabetic State.
What This Means in Plain Language
The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 330 individuals.
With several hundred people or more, it is a fairly large study for this kind of research.
Its findings take up roughly 4 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2016 (PloS one), a journal based in United States.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.