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Effect of zinc plus multivitamin supplementation on growth in school children.
Plain-language guide to PMID 27083763 (2016): single-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Key Facts
- PMID
- 27083763
- Journal
- Pediatrics international : official journal of the Japan Pediatric Society
- Year
- 2016
- Study type
- Randomized Controlled Trial
- Authors
- Rerksuppaphol S et al. (2 authors)
- DOI
- 10.1111/ped.13011
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement), published as a randomized controlled trial.
Zinc and multiple vitamins are essential for growth.
Zinc and vitamin deficiency is very common in developing countries.
Who Took Part
The age groups tagged for this paper are young children, children and teenagers, both men and women.
A randomized controlled trial was conducted in healthy 4-13-year-old Thai schoolchildren attending public school in central Thailand.
How the Study Was Run
The researchers set it up as a randomized, single-blind and placebo-controlled study.
Because people in this Vitamin D, K2, Magnesium and Zinc study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.
Only one side, usually the participants, was kept unaware of whether Vitamin D, K2, Magnesium and Zinc was given.
A placebo (an inactive look-alike) gave the Vitamin D, K2, Magnesium and Zinc group a baseline to be compared against.
Primary outcome was change in height from baseline to the end of the study.
Secondary outcomes were change in weight, body mass index, waist and hip circumferences and waist-to-height ratio.
An intention-to-treat analysis was performed.
What Was Measured
The subject headings attached to it are Body Height, Child Development, Dietary Supplements, Schools, Thailand, Vitamins and Zinc.
Author keywords: growth and multivitamin.
What This Means in Plain Language
The paper is a randomized, single-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc and Copper (Supplement).
Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2016 (Pediatrics international : official journal of the Japan Pediatric Society), a journal based in Australia.
More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Copper (Supplement) compound page, all human trials.
Our Notes on the Compounds
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Copper (Supplement): The active site of cytochrome c oxidase is described as containing copper ions that are essential for electron transfer.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.