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Vitamin D insufficiency and deficiency in mexican patients with systemic lupus erythematosus: Prevalence and relationship with disease activity.
Plain-language guide to PMID 27084269 (2018): observational study of Vitamin D, K2, Magnesium and Zinc in 137 women, lupus (sle).
Key Facts
- PMID
- 27084269
- Journal
- Reumatologia clinica
- Year
- 2018
- Study type
- Observational Study
- Authors
- García-Carrasco M et al. (10 authors)
- DOI
- 10.1016/j.reuma.2016.02.013
What This Study Did, in Plain Language
What Was Tested
The paper reports a study of Vitamin D, K2, Magnesium and Zinc in the context of lupus (sle), published as an observational study.
To determine and compare the prevalence of vitamin D insufficiency and deficiency in patients with systemic lupus erythematosus (SLE) with and without disease activity.
Who Took Part
The study group was 137 women.
PubMed indexes the participants as adults and middle-aged adults, women only.
The researchers made a comparative, observational, cross-sectional, prospective study of 137 women with SLE according to American College of Rheumatology criteria.
Patients with chronic kidney disease, cancer, hyperparathyroidism, pregnancy, and lactation were excluded.
How the Study Was Run
Disease activity was assessed using the MEX-SLEDAI score: a score of ≥3 was considered as disease activity.
Data were collected on diabetes mellitus, the use of corticosteroids, chloroquine, and immunosuppressants, photoprotection and vitamin D supplementation.
Vitamin D levels were measured by chemiluminescent immunoassay: insufficiency was defined as serum 25-hydroxyvitamin D <30ng/ml and deficiency as <10ng/ml.
What Was Measured
PubMed files the paper under topics including Cross-Sectional Studies, Disease Progression, Lupus Erythematosus, Systemic, Mexico, Prevalence, Risk Factors and Vitamin D Deficiency.
Author keywords: Deficiencia, Insufficiency, Insuficiencia, Lupus eritematoso sistémico, Systemic lupus erythematosus and Vitamina D.
What This Means in Plain Language
This is an observational study of Vitamin D, K2, Magnesium and Zinc in 137 women in people with lupus (sle).
Its findings take up roughly 7 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.
The publication is from 2018 (Reumatologia clinica), a journal based in Spain.
More context: the Vitamin D, K2, Magnesium and Zinc compound page, Lupus (SLE) research.
Our Notes on the Compound
Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.
Related Pages
Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.