Lean Seafood Intake Reduces Postprandial C-peptide and Lactate Concentrations in Healthy Adults in a Randomized Controlled Trial with a Crossover Design.

What Was Tested

This randomized controlled trial looks at C-Peptide.

The researchers aimed to elucidate whether diet-induced altered carbohydrate metabolism could be a contributing factor to the previously observed different lipoprotein patterns.

Who Took Part

The abstract describes 20 adults taking part.

PubMed indexes the participants as middle-aged adults, both men and women.

This was a secondary outcome and explorative randomized controlled trial with a crossover design in 20 healthy adults (7 men and 13 women) that were 50.6 ± 3.4 (mean ± SEM) y old, weighed 75.7 ± 2.5 kg, and had a body mass index (BMI, in kg/m(2)) of 25.6 ± 0.7.

How the Study Was Run

The researchers set it up as a randomized and crossover study.

Because people in this C-Peptide study were split into groups at random, differences between the groups are less likely to reflect who happened to join each one.

Each person switched between C-Peptide and the comparison at some point, usually with a gap in between.

The diets varied in the main protein sources; 60 energy% of total protein was from either lean seafood or nonseafood sources.

What Was Measured

The subject headings attached to it are Blood Glucose, C-Peptide, Carbohydrate Metabolism, Cholesterol, HDL, Diet, Dietary Fats and Dietary Proteins.

The authors tagged it with the keywords dietary protein sources, glucose metabolism, insulin sensitivity, lactate, lean seafood and postprandial.

What This Means in Plain Language

The paper is a randomized and crossover study of C-Peptide in 20 adults.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

The abstract goes on to report its results in about 5 sentences; this page does not restate them, so read the paper for the findings and their limits.

The publication is from 2016 (The Journal of nutrition), a journal based in United States.

More context: the C-Peptide compound page, all human trials.