[Effect of arterial infusion with methylene blue during total mesorectal excision on urination function and sexual function in male patients with rectal cancer]

Plain-language guide to PMID 27112475 (2016): randomized controlled trial study of Methylene blue (non-peptide stack partner) in 68 patients, sexual function & libido (women and men).

Key Facts

PMID: 27112475
Journal: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
Year: 2016
Study type: Randomized Controlled Trial
Authors: He X et al. (4 authors)

What This Study Did, in Plain Language

What Was Tested

Researchers studied Methylene blue (non-peptide stack partner) in the context of sexual function & libido (women and men) in this randomized controlled trial publication.

To explore the effect of arterial infusion with methylene blue during total mesorectal excision (TME) for better preservation of pelvic autonomic nerve on urination function and sexual function in male patients with rectal cancer.

Who Took Part

The abstract describes 68 patients taking part.

PubMed tags the participants as men only.

A total of 68 male rectal cancer patients from Zhejiang Xiaoxing People's Hospital and 44 male rectal cancer patients from Guangdong Zhongshan Chenxinghai Hospital between June 2013 and June 2015 were prospectively enrolled.

All the patients underwent TME.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Methylene blue (non-peptide stack partner) and who got the comparison, which limits bias.

Intra-operational lymph node removal and postoperative urination and sexual function (erection and ejaculation) were compared between two groups.

What Was Measured

PubMed files the paper under topics including Digestive System Surgical Procedures, Infusions, Intra-Arterial, Lymph Node Excision, Methylene Blue, Postoperative Period, Rectal Neoplasms and Rectum.

What This Means in Plain Language

The paper is a randomized study of Methylene blue (non-peptide stack partner) in 68 patients in people with sexual function & libido (women and men).

Its findings take up roughly 9 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2016 (Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery), a journal based in China.

More context: the Methylene blue (non-peptide stack partner) compound page, Sexual function & libido (women and men) research.

Our Notes on the Compound

Methylene blue (non-peptide stack partner): Described as an electron cycler, not just a dye.

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.