Short-term Administration of Alphacalcidol is Associated with More Significant Improvement of Muscular Performance in Women with Vitamin D Deficiency Compared to Native Vitamin D.

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc, published as a randomized controlled trial.

Aim: the researchers aim to investigate the effect of short-term treatment with native VD (cholecalciferol) or alphacalcidol on the muscular function and physical performance in women with vitamin D deficiency.

Why It Was Studied

Material and methods: the researchers analysed 178 women with VD deficiency, defined as serum 25-hydroxyVD-25OHD concentration below 30 ng/ml.

The researchers recorded the grip-strength and the results of the chair-rise test (CRT) and timed-up-and-go test (TUG).

Who Took Part

The study group was 178 women.

The age groups tagged for this paper are adults, middle-aged adults, older adults and people over 80, women only.

How the Study Was Run

The researchers set it up as a randomized study.

Random assignment meant chance, not the researchers, decided who got Vitamin D, K2, Magnesium and Zinc and who got the comparison, which limits bias.

What Was Measured

The researchers recorded the grip-strength and the results of the chair-rise test (CRT) and timed-up-and-go test (TUG).

PubMed files the paper under topics including Hand Strength, Hydroxycholecalciferols, Muscle, Skeletal and Vitamin D Deficiency.

What This Means in Plain Language

The paper is a randomized study of Vitamin D, K2, Magnesium and Zinc in 178 women.

The publication is from 2016 (Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association), a journal based in Germany.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.