Vitamin D deficiency and pregnancy rates following frozen-thawed embryo transfer: a prospective cohort study.

What Was Tested

This observational study looks at Vitamin D, K2, Magnesium and Zinc.

What is the effect of vitamin D deficiency on the pregnancy rates following frozen embryo transfer (FET)?.

Vitamin D deficiency does not affect pregnancy rates in FET cycles.

Who Took Part

The abstract describes 280 patients taking part.

PubMed indexes the participants as adults, women only.

A total of 280 consecutive patients, who had at least one blastocyst frozen and were planned for a FET, were enrolled in the study following detailed information and signing of a written informed consent.

How the Study Was Run

This study is the first prospective observational cohort study from the Centre for Reproductive Medicine at the University Hospital of Brussels.

The duration of the study was 1 year.

Serum analysis of 25-OH vitamin D was measured on the day of embryo transfer, and the impact of vitamin deficiency was investigated on reproductive outcomes.

What Was Measured

Ethnicity in relation to vitamin D status was not assessed, given that the vast majority of patients included in their study were Caucasian, whereas the researchers did only assess 25-OH vitamin D levels and not bioavailable vitamin D.

The subject headings attached to it are Cryopreservation, Embryo Implantation, Embryo Transfer, Infertility, Female, Pregnancy Outcome, Pregnancy Rate and Vitamin D.

The authors tagged it with the keywords blastocyst and frozen embryo transfer.

What This Means in Plain Language

This is an observational study of Vitamin D, K2, Magnesium and Zinc in 280 patients.

Results are reported in around 7 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2016 (Human reproduction (Oxford, England)), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page, all human trials.