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Three week dietary intervention using apricots, pomegranate juice or/and fermented sour sobya and impact on biomarkers of antioxidative activity, oxidative stress and erythrocytic glutathione transferase activity among adults.

Plain-language guide to PMID 27175476 (2016): randomized controlled trial of Polyphenols in 35 adults.

Key Facts

PMID
27175476
Journal
Nutrition journal
Year
2016
Study type
Randomized Controlled Trial
Authors
Gouda M et al. (4 authors)
DOI
10.1186/s12937-016-0173-x

What This Study Did, in Plain Language

What Was Tested

Researchers studied Polyphenols in this randomized controlled trial publication.

Two way analysis of variance (ANOVA) was conducted and included the main effects of treatment, time and treatment x time interaction.

The study was approved by the research ethical committee of the Ministry of Health & population, Egypt.

Who Took Part

According to the abstract, 35 adults were involved.

PubMed indexes the participants as young adults and adults, both men and women.

The supplements were analyzed chemically for (PP) contents and total antioxidative activities and microbiologically for selected bacteria and yeast counts.

How the Study Was Run

The design is described as randomized.

The adults were allocated by chance, so the Polyphenols group and the comparison group should start out alike.

Blood and urine samples were collected at days zero and 22 of the dietary intervention.

The blood samples were assayed for plasma antioxidative activities and for erythrocytic glutathione transferase activity (E-GST).

Urine samples were analyzed for the excretions of total PP, antioxidative activity and thiobarbituric acid reactive substances (TBARS).

What Was Measured

The subject headings attached to it are Antioxidants, Ascorbic Acid, Biomarkers, Creatinine, Diet, Egypt and Erythrocytes.

The authors tagged it with the keywords Antioxidative activity, Erythrocytic glutathione- S-transferase, Human trial, Oxidative stress, Pomegranate juice and Sobya.

What This Means in Plain Language

The paper is a randomized study of Polyphenols in 35 adults.

With fewer than 40 people, it is a small study, so it is better read as an early signal for further research than as a settled answer.

Results are reported in around 5 sentences of the abstract; we leave them to the paper itself rather than summarise them.

The publication is from 2016 (Nutrition journal), a journal based in England.

More context: all human trials.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.