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Effect of vitamin D supplementation, directly or via breast milk for term infants, on serum 25 hydroxyvitamin D and related biochemistry, and propensity to infection: a randomised placebo-controlled trial.

Plain-language guide to PMID 27184759 (2016): double-blind randomized controlled trial of Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84).

Key Facts

PMID
27184759
Journal
The British journal of nutrition
Year
2016
Study type
Randomized Controlled Trial
Authors
Chandy DD et al. (8 authors)
DOI
10.1017/S0007114516001756

What This Study Did, in Plain Language

What Was Tested

The paper reports a study of Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84), published as a randomized controlled trial.

The researchers assessed the effect of vitamin D supplementation on related biochemistry, infection and dentition of the infant.

All babies received 15 min of sun exposure (unclothed) during massage.

Who Took Part

By PubMed's age tags, the people studied were infants, both men and women.

How the Study Was Run

The design is described as randomized, double-blind and placebo-controlled.

The participants were allocated by chance, so the Vitamin D, K2, Magnesium and Zinc group and the comparison group should start out alike.

Blinding on both sides kept the participants and researchers unaware of who received Vitamin D, K2, Magnesium and Zinc.

Some participants received a placebo instead of Vitamin D, K2, Magnesium and Zinc, giving a reference point.

What Was Measured

The researchers assessed the effect of vitamin D supplementation on related biochemistry, infection and dentition of the infant.

Topics PubMed links to this paper include Cholecalciferol, Dietary Supplements, Infant Formula, Infant Nutritional Physiological Phenomena, Infections, Lactation and Maternal Nutritional Physiological Phenomena.

Author keywords: 25(OH)D 25-hydroxyvitamin D, IQR interquartile range, Infants, PTH parathyroid hormone, Sunshine and Vitamin D.

What This Means in Plain Language

The paper is a randomized, double-blind and placebo-controlled study of Vitamin D, K2, Magnesium and Zinc and Parathyroid Hormone (PTH 1-84).

The publication is from 2016 (The British journal of nutrition), a journal based in England.

More context: the Vitamin D, K2, Magnesium and Zinc compound page and the Parathyroid Hormone (PTH 1-84) compound page, all human trials.

Our Notes on the Compounds

Vitamin D, K2, Magnesium and Zinc: Magnesium is described as required for AMPK to function.

Parathyroid Hormone (PTH 1-84): The 84-amino-acid hormone that raises blood calcium; full-length PTH (Natpara) has been used in hypoparathyroidism. Teriparatide is its 1-34 fragment.

Related Pages

Source: PubMed record. This explanation is written by PeptideWhiz from the public record. For research and education only. Not medical advice; no dosing information is given.