Intrauterine administration of human chorionic gonadotropin (hCG) for subfertile women undergoing assisted reproduction.

What It Covers

This meta-analysis looks at hCG (human chorionic gonadotropin).

Assisted reproduction refers to procedures involving the in vitro handling of both human gametes and represents a key option for many subfertile couples.

Most women undergoing assisted reproduction treatment will reach the stage of embryo transfer (ET) but the proportion of embryos that successfully implant following ET has remained small since the mid-1990s.

Who the Included Studies Covered

By PubMed's age tags, the people studied were adults, women only.

How the Review Was Done

The researchers performed a comprehensive literature search of the Cochrane Gynaecology and Fertility Group Specialised Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, CINAHL, PsycINFO, registers of ongoing trials andreference lists of all included studies and relevant reviews (from inception to 10 November 2015), in consultation with the Cochrane Gynaecology and Fertility Group Trials Search Co-ordinator.

What Was Measured

The researchers included all randomised controlled trials (RCTs) evaluating intrauterine administration of hCG around the time of ET in this review irrespective of language and country of origin.

Two authors independently selected studies, assessed risk of bias, extracted data from studies and attempted to contact the authors where data were missing.

PubMed files the paper under topics including Abortion, Spontaneous, Chorionic Gonadotropin, Embryo Transfer, Infertility, Female, Live Birth, Pregnancy Rate and Reproductive Control Agents.

What This Means in Plain Language

This is a meta-analysis of hCG (human chorionic gonadotropin).

Its findings take up roughly 16 sentences of the abstract and are left out here on purpose; the source paper is the place to read them.

The publication is from 2016 (The Cochrane database of systematic reviews), a journal based in England.

More context: the hCG (human chorionic gonadotropin) compound page, all human trials.